Genetics & Genomics

Emerging Role of Nutri-Epigenetics in Inflammation and Cancer

Paule V. Joseph

Sarah K. Abey

Wendy A. Henderson

biology of cancer, epigenetics, nutri-epigenetics, nutrition, DNA methylation
ONF 2016, 43(6), 784-788. DOI: 10.1188/16.ONF.784-788

Nutrition is a factor involved in inflammation and a modulator of risk toward some cancers, and the complexity of linkages between dietary components and epigenetics mechanisms (e.g., DNA methylation, histone modification, chromatin remodeling) may affect the inflammation phenotype and the development of cancer. An increasing number of studies support the role of diet in cancer development, prevention, and treatment. Although current knowledge regarding nutri-epigenetics is expanding, more work is needed, and nurse scientists have the potential to significantly contribute to the expansion of this knowledge.

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