A Phase I Study Examining the Feasibility and Safety of an Aerobic Exercise Intervention in Patients With Rectal Cancer During and After Neoadjuvant Chemoradiotherapy
Andria R. Morielli, MSc; Nawaid Usmani, MD; Normand G. Boulé, PhD; Keith Tankel, MD; Diane Severin, MD; Tirath Nijjar, MD; Kurian Joseph, MD; and Kerry S. Courneya, PhD
ONF
10.1188/16.ONF.352-362
Description
Purpose/Objectives: To assess the feasibility and safety of an aerobic exercise intervention in patients with rectal cancer during and after neoadjuvant chemoradiotherapy (NACRT).
Design: A prospective, single-group design with assessments at pre-NACRT, post-NACRT, and presurgery.
Setting: The Cross Cancer Institute and University of Alberta in Edmonton, Canada.
Sample: 18 patients with rectal cancer scheduled to receive long-course NACRT followed by definitive surgery.