Toxic Epidermal Necrolysis

Case Study: M.J. is a 57-year-old man diagnosed with stage IIb squamous cell carcinoma of the left tonsil. At the time of diagnosis, he underwent a radical neck dissection. Two months later, he started radiation. Amifostine was administered via IV 30 minutes prior to radiation for the purpose of decreasing the incidence of xerostomia and mucositis. M.J. also was using artificial saliva and Aquaphor® (Eucerin) as needed. In the outpatient infusion area, M.J. received 500 ml 0.9% sodium chloride IV infusion over 60 minutes, ondansetron 8 mg IV piggyback over 15 minutes, and amifostine 440 mg (200 mg/m²) IV piggyback over 15 minutes.