On a high-volume academic ambulatory chemotherapy unit, a medication error triggered an evidence-based practice nursing work group to initiate a pilot “chemo checker” role as part of a new chemotherapy verification process. The group implemented two interventions to minimize nurse distractions and a 17-point chemotherapy verification label. An independent verification role was created to perform the first check for chemotherapy. Six months into the pilot project, medication administration errors and nurses’ distractions during the chemotherapy verification process decreased, and nurses’ perception of safety during the process increased (N = 22).