Lymphedema can be an unfortunate side effect of cancer treatment. It is a chronic condition that, if ignored, can lead to disfigurement, immobilization, and severe infections. Several methods for assessing lymphedema are used in clinical practice, and some of these methods are reported in the literature. Although these methods can be useful and provide meaningful data, they also can be time consuming, complicated, expensive, or difficult to communicate to patients or other healthcare providers. The comparative circumferential measurement method (CCMM) is easy to perform, requires only a tape measure and a calculator, and allows for use of the contralateral limb as a control. Results can be calculated immediately so that patients can be given prompt feedback. In clinical settings, CCMM is a simple, efficient, and meaningful technique for assessing lymphedema.