Peripheral Neuropathy Search Strategy and Results

Initial references prior to update: 19

Databases searched for update: PubMed, CINAHL

Search results of literature retrieved 3/1/2009 – 1/1/2019

  • PubMed
    • ((neuropath*[ti] OR neurotoxic*[ti]) AND (cancer[ti] OR chemotherap*[ti] OR neoplasms[majr])) OR ("Peripheral Nervous System Diseases/chemically induced"[Majr] OR "Peripheral Nervous System Diseases/diet therapy"[Majr] OR "Peripheral Nervous System Diseases/drug therapy"[Majr] OR "Peripheral Nervous System Diseases/nursing"[Majr] OR "Peripheral Nervous System Diseases/prevention and control"[Majr] OR "Peripheral Nervous System Diseases/rehabilitation"[Majr] OR "Peripheral Nervous System Diseases/therapy"[Majr]) OR ((neuropath* OR neurotoxic*) AND (balanc* OR falls OR falling OR strength OR “Activities of Daily Living” OR “occupational therapy” OR “physical therapy” OR “assistive device” OR “assistive devices” OR rehabilitation) AND (cancer OR neoplasms OR oncolog* OR chemotherapy*)) AND (("2009/01/01"[PDAT] : "2019/01/01"[PDAT]) AND "humans"[MeSH Terms] AND English[lang] AND cancer[sb])
    • 4,132 citations retrieved
  • CINAHL:
    • ((TI neuropath* OR TI neurotoxic*) AND (TI cancer OR TI chemotherap* OR neoplasm*)) OR (MM "Peripheral Nervous System Diseases/CI/DH/DT/NU/PC/RH/TH") OR ((neuropath* OR neurotoxic*) AND (balanc* OR falls OR falling OR strength OR “Activities of Daily Living” OR “occupational therapy” OR “physical therapy” OR “assistive device” OR “assistive devices” OR rehabilitation) AND (cancer OR neoplasms OR oncolog* OR chemotherapy*))
    • Limiters: English language; clinical queries: therapy - High Sensitivity, Therapy - High Specificity, Therapy - Best Balance; Human
    • 586 citations retrieved

296 titles were selected for full article review.

119 final studies were included after the removal of duplicates and studies that did not meet inclusion criteria and the addition of manuscripts retrieved in other topics meeting peripheral neuropathy-specific criteria.

Inclusion Criteria

  1. They were full research reports, systematic reviews, guidelines, or meta-analyses.
  2. Study must report results of measurement of peripheral neuropathy symptoms.
  3. The study examines an intervention aimed at affecting symptoms of peripheral neuropathy.
  4. Study sample must include patients with cancer.
  5. As of 1/1/2016, additional inclusions are (a) sample size of at least 40 or 20 per study group, and (b) for complex interventions, the description of the intervention must be sufficient to identify the components of that intervention.

Exclusion Criteria

  1. Grey literature
  2. Descriptive studies
  3. Studies involving general neuropathic pain only
  4. Studies not associated with treatment-related peripheral neuropathy