Chiarioni, G., Whitehead, W.E., Pezza, V., Morelli, A., & Bassotti, G. (2006). Biofeedback is superior to laxatives for normal transit constipation due to pelvic floor dyssynergia. Gastroenterology, 130, 657–664.
To assess long-term (24-month) efficacy of biofeedback versus laxatives and bowel education.
Biofeedback training was provided in five 30-minute classes over five weeks. Similarly, laxative plus bowel education was provided in five 30-minute bowel training classes over five weeks. Those patients also took 14.6 to 22.9 g/kg of polyethylene glycol for the first six months; after six months, patients took the dose BID.
Tertiary gastroenterology clinic in Verona, Italy
This was a randomized, controlled trial.
Biofeedback should be the treatment of choice for PFD-induced constipation.