PURPOSE: To summarize evidence and provide antiemetic recommendations for the prevention of acute chemotherapy-induced nausea and vomiting (CINV) among children receiving chemotherapy
TYPES OF PATIENTS ADDRESSED: Pediatric oncology patients receiving chemotherapy
RESOURCE TYPE: Evidence-based guideline
PROCESS OF DEVELOPMENT: Articles were identified through a search of databases and independently reviewed and scored by three to four members of the Guideline Development Panel using the Appraisal of Guidelines for Research and Evaluation (AGREE) instrument. Evidence summary tables were compiled and reviewed by two panel members before an article was considered for inclusion in a meta-analysis completed by the panel.
DATABASES USED: Medline, Embase, Cochrane Central Register of Controlled Trials (CCTR), Allied and Complementary Medicine (AMED), Health Technology Assessment (HTA), National Health Service Economic Evaluation Database (NHS EED), EBSCOhost, and Google
KEYWORDS: N/A
INCLUSION CRITERIA: Full-text articles published in English or French reporting pediatric data separately, reporting emetogenicity of the chemotherapy used, providing an explicit or implicit definition of complete acute antineoplastic-induced nausea and vomiting (AINV) response, and reporting the complete acute AINV response rate as a proportion or percentage
EXCLUSION CRITERIA: Articles only available as abstracts.