Ismail, M.A., Kamal, A.M., Ghobashy, S., Al Baz, A.G., & Roshdy, M. (2015). Comparison of pain control during Trus guided biopsies between basal peri-prostatic local infiltration anesthesia versus combined topical anal lignocaine ointment and local infiltration anesthesia. Journal of the Egyptian Society of Parasitology, 45, 285–289.
To compare two techniques for pain relief with transrectal ultrasonography (TRUS)-guided biopsies
Patients undergoing prostate biopsies were randomized to receive either local infiltration anesthesia alone or a combination of local anesthesia and lignocaine 5% ointment to the anal rind, canal, and anterior rectal wall. Patients were asked to rate pain during insertion, during infiltration, and after biopsy.
Randomized trial
Patients who received a combination of local and topical anesthesia reported significantly less pain (p = 0.005) at all stages of the procedure.
The combination of a local anesthetic infusion with a topical anesthetic may provide better pain control during biopsy.
The combination of anesthetic infiltration and a local topical anesthetic may reduce pain during biopsy.