Lajolo, P.P., De Camargo, B., & Del Giglio, A. (2009). Omission of day 2 of antiemetic medications is a cost saving strategy for improving chemotherapy-induced nausea and vomiting control results of a randomized phase III trial. American Journal of Clinical Oncology, 32, 23–26.
To evaluate the effect of omitting day 2 administration of granisetron in the treatment of chemotherapy-induced nausea and vomiting (CINV)
The study was conducted at a single outpatient setting in Brazil.
All patients were in active treatment.
This was a randomized, placebo-controlled, double-blind trial.
Differences in rates of complete protection from nausea and vomiting in this study were unclear and difficult to interpret because different groups experienced better CINV control at different time points.
No clear conclusions can be drawn from this study.