Loening-Baucke, V., & Pashankar, D.S. (2006). A randomized, prospective, comparison study of polyethylene glycol 3350 without electrolytes and milk of magnesia for children with constipation and fecal incontinence. Pediatrics, 118, 528–535.
To compare and evaluate the efficacy, safety, acceptance, and one-year outcome of two laxatives, polyethylene glycol (PEG) without electrolytes and milk of magnesia (MOM).
Patients were randomly assigned to intervention with PEG 3350 without electrolytes (Miralax®) or MOM by drawing a sealed envelope. Patients initially received 0.7 g/kg of PEG or 2 ml/kg of MOM daily.
Children’s Hospital of Iowa
Randomized controlled trial
PEG and MOM are effective and safe in long-term treatment, with PEG having better acceptance.