Amitriptyline is a tricyclic antidepressant that research has identified as being useful for the treatment of peripheral neuropathy symptoms and neuropathic pain. For the non-cancer population, it has been used as a treatment for eating disorders and migraine headaches. Amitriptyline is available as a tablet to take by mouth. It may take weeks to build up in the system in order for one to feel the full benefits of the drug, and suddenly stopping use can cause symptoms of withdrawal. Amitryptyline has been evaluated for its effects in peripheral neuropathy and, as an antidepressant, it has relevance for the topic of depression.