Röper, B., Kaisig, D., Auer, F., Mergen, E., & Molls, M. (2004). Thêta-cream versus Bepanthol lotion in breast cancer patients under radiotherapy. A new prophylactic agent in skin care? Strahlentherapie und Onkologie, 180, 315–322.
Thêta-cream was compared with standard skin care using Bepanthol (Bepanthen) lotion to prevent acute radiation therapy (RT) side effects in skin tissue.
Patients were randomly assigned to use Thêta-Cream (GM Glucan, Hydroxyprolisilan C, Matrixyl) (arm A) or Bepanthol lotion (dexpanthenol) (arm B) during RT. Medication was applied lightly to the treatment field twice daily starting within one week before beginning RT. Patients were requested to wash irradiated skin gently with care to skin marks. No other prophylactic topical treatment was allowed.
The study was a randomized, blinded, controlled trial.
In direct comparison with dexpanthenol-containing lotion, no advantage for Thêta-Cream was found.