Scotté, F., Tourani, J.M., Banu, E., Peyromaure, M., Levy, E., Marsan, S., . . . Oudard, S. (2005). Multicenter study of a frozen glove to prevent docetaxel-induced onycholysis and cutaneous toxicity of the hand. Journal of Clinical Oncology, 23, 4424–4429.
To determine if frozen glove (FG) treatment prevents docetaxel-induced onycholysis and skin toxicity
PHASE OF CARE: Active treatment
The findings suggest that regional cooling may be of benefit to prevent nail toxicity associated with docetaxel treatment.
Regional cooling may have some benefit to reduce the incidence of nail and skin toxicities associated with chemotherapy. Nurses need to be aware of patients who have cold intolerance because of peripheral neuropathies or other reasons, but this appears to be a low-risk intervention that can be helpful.