Shen, J., Wenger, N., Glaspy, J., Hays, R.D., Albert, P.S., Choi, C., & Shekelle, P.G. (2000). Electroacupuncture for control of myeloablative chemotherapy-induced emesis: A randomized controlled trial. JAMA, 284, 2755-2761.
To compare the effectiveness of electroacupuncture, minimal needling and mock electrical stimulation, or antiemetic medications alone in controlling emesis among patients undergoing highly emetogenic chemotherapy
Participants were randomly assigned to one of three groups.
Participants were from an inpatient unit at a tertiary hospital with a comprehensive cancer center. Patients were recruited from oncology clinics.
The study design was random, without stratification.
Investigators recorded the total number of emetic episodes during the five-day study period and the proportion of emesis-free days across the treatment groups.