Spahn, G., Choi, K.E., Kennemann, C., Ludtke, R., Franken, U., Langhorst, J., . . . Dobos, G.J. (2013). Can a multimodal mind-body program enhance the treatment effects of physical activity in breast cancer survivors with chronic tumor-associated fatigue? A randomized controlled trial. Integrative Cancer Therapies, 12, 291–300.
To evaluate a multimodal mind-body program (MMMT) compared to walking effect on fatigue in women with stage I–IIIA breast cancer
Participants in the intervention group underwent six hours of training in meditation, whole-food cooking, naturopathic strategies, and mindfulness by a multidisciplinary team. A sports therapist supervised a walking program in weeks 1, 3, and 10. Participants were encouraged to walk at home three times per week for 30 minutes. Participants in the control group also underwent a sports therapist-supervised walking program in weeks 1, 3, and 10. They also were encouraged to walk at home three times per week for 30 minutes.
Unusual fatigue in the last week and last month was improved in both groups with no group differences. Anxiety in the MMMT group was improved compared to the control group (p = .043) during treatment but was not maintained in follow-up (p = .422). Both groups showed overall anxiety improvement. Reported pain between groups was improved in MMMT at follow-up compared to control (p = .031). Menopausal symptoms decreased in both groups. No significant side effects were seen.
A home-based exercise program showed improvement in reported fatigue. The addition of a mind-body component showed no additional benefit.
Home-based exercise is a reasonable and safe option for patients experiencing cancer-related fatigue.