Weinbroum, A.A. (2005). Superiority of postoperative epidural over intravenous patient-controlled analgesia in orthopedic oncologic patients. Surgery, 138, 869–876.
To compare patient-controlled analgesia (PCA) post-operative pain control by IV morphine versus epidural ropivacaine plus fentanyl analgesia in patients undergoing lower-body oncologic orthopedic procedures attributed to bone malignancy
Patients were assigned randomly. There was no control group.
Postoperative ropivacaine plus fentanyl via PCEA reduces pain better and affords better subjective feelings than morphine IV PCA after resection of bone malignancy carried out under combined general and epidural anesthesia.