Yekta, Z.P., Ebrahimi, S.M., Hosseini, M., Nasrabadi, A.N., Sedighi, S., Surmaghi, M.H., & Madani, H. (2012). Ginger as a miracle against chemotherapy-induced vomiting. Iranian Journal of Nursing and Midwifery Research, 17(5), 325–329.
To evaluate the effect of the ginger plant on chemotherapy-induced vomiting
The intervention persisted for six days starting three days before the chemotherapy session. During this period, all participants took four 250 mg capsules (Zintoma) at six-hour intervals (1 g per day) complemented by the routine antiemetic regimen, including Kytril, or granisetron hydrochloride tablets, (1 mg per day) and dexamethasone ampoules (8 mg per day). A self-made, two-part, self-reporting instrument was used to measure the number of vomiting cases in both the groups. Vomiting times were recorded in the instruments each night just before sleep.
Randomized, double-blind, placebo-controlled clinical trial
A self-made, two-part, self-reporting instrument was used to measure the number of vomiting cases in both the groups. This instrument was a reliable standard table that has been used in various studies.
The results of this randomized, controlled trial showed that ginger alleviated nausea and vomiting in patients in the ginger arm compared to the placebo group. Ginger could be a promising antiemetic herbal remedy; however, its positive effects could be dose-related or specific agent-related. Therefore, we need further evidence, including multiagent chemotherapy with different types of cancers.
The nursing implication was confined to teaching patients and their families about the ginger capsules.