Bryophyllum pinnatum is a perennial herb that has been used in folklore medicine in several countries. This herb contains a wide range of chemical compounds such as alkaloids, flavonoids, steroids, lipids, and organic acids. Various plant extracts have central nervous system depression, analgesia, antimicrobial, anti-inflammatory, and sedative effects. Bryophyllum pinnatum has been studied for its effect on sleep-wake disturbances among patients with cancer.