Cocculine is a homeopathic medicinal product used for nausea and motion sickness in France. Cocculine consists of four homeopathic components: Cocculus indicus 4 CH, Tabacum 4 CH, Nux vomica 4 CH, and Petroleum 4 CH. It has been evaluated for the management of chemotherapy-induced nausea and vomiting (CINV) in patients with cancer.