Juice from grapes is rich in flavonoids, which have antioxidant properties and act as scavengers of free radicals. This may inhibit related damage to cells. The effect of grape juice ingestion as an adjunct to antiemetics was tested in patients with cancer for management of chemotherapy-induced nausea and vomiting (CINV). Flavonoids were hypothesized to reduce the severity of chemotherapy-related cell damage, thereby reducing one of the possible stimuli for CINV.