Vitamin E is a fat-soluble vitamin found in seeds, nuts, leafy vegetables, and vegetable oils. It is a type of antioxidant and helps prevent cell damage caused by free radicals (highly reactive chemicals). It is being studied in the prevention and treatment of some types of cancer. Vitamin E has been used as an oral or parenteral supplement and as a solution for topical application. Vitamin E has been examined in management of diarrhea, mucositis, peripheral neuropathy, skin effects, cognitive impairment, and hot flashes.