Supplementary Material for ONS Guidelines™ for Cancer Treatment-Related Radiodermatitis

Table of Contents

1. PICO questions
2. Search strategies
3. Evidence risk of bias figure
4. Evidence profiles

• Deodorant/antiperspirant in addition to normal washing vs. normal washing
• Aloe vera vs. standard of care
• Emu oil vs. standard of care
• Oral curcumin vs. standard of care
• Topical non-steroidal interventions vs. standard of care
• Calendula vs. standard of care
• Topical steroidal creams vs. standard of care
• Semi-permeable dressings vs. standard of care

5. Forest plots

• Deodorant/antiperspirant in addition to normal washing vs. normal washing: Grade 2 radiodermatitis
• Deodorant/antiperspirant in addition to normal washing vs. normal washing: Grade 3 radiodermatitis
• Topical non-steroidal interventions vs. standard of care: Grade 2 or higher radiodermatitis
• Topical non-steroidal interventions vs. standard of care: Pruritis
• Calendula vs. standard of care: Grade 2 or higher radiodermatitis
• Topical steroidal creams vs. standard of care: Grade 2 or higher radiodermatitis
• Topical steroidal creams vs. standard of care: Moist desquamation
• Semi-permeable dressings vs. standard of care: Grade 2 or higher radiodermatitis
• Semi-permeable dressings vs. standard of care: Moist desquamation
• Semi-permeable dressings vs. standard of care: Adverse events leading to discontinuation

6. Characteristics of included studies