This article explores the relationships among cancer care, financial challenges, and mental health, emphasizing the growing significance of addressing these interconnected issues. Increased frequency of cancer diagnoses and improved treatment options have resulted in higher survival rates, highlighting emerging challenges. Disparities exist among specific populations, underscoring the need for targeted interventions. Current interventions and policy strategies highlight gaps in addressing financial toxicity and health-related quality of life. Future research should include developing tailored interventions and policies that consider the complex interplay among cancer care, financial challenges, and mental health.