Topical Anesthetics
The topical use of anesthetics consists of applying an anesthetic agent, such as lidocaine, to the skin or mucosa. In cancer care, topical anesthetics are used to reduce the acute pain of diagnostic procedures, such as biopsy, and postoperative incisions. Topical anesthetics have been examined in chronic pain as well
Tibolone
Tibolone is an anabolic steroid. Tibolone has been examined in the treatment of hot flashes.
Thyrotropin Releasing Hormone (TRH)
TRH is a hormone that stimulates release of thyroid-stimulating hormone from the pituitary gland. TRH has been studied in patients with cancer for its effect on fatigue.
Theta Cream
Theta cream contains glucan, hydroxyprolisilane, and matrixyl. Glucan is a polysaccharide molecule, some types of which occur in nature in plants, grains, baker's yeast, and medicinal mushrooms. Some of these have modulating effects on the immune system. Hydroxyprolisilane is a component of several cosmetic skin care products that has properties of tissue regeneration and strengthening of collagen and elastin fibers. Matrixyl is in some anti-aging creams and serums.
Therapeutic Touch
Therapeutic touch (TT) or healing touch is an energy therapy where the practitioner’s hands move through the patient’s energy field to assess and treat energy field imbalances (Shames & Keegan, 2000). The specially trained practitioner deliberately “centers” intention from an external focus to an internal focus of calm, then moves his or her hands over the patient’s body, but does not actually touch the body. TT has been studied as an intervention for anxiety and pain in patients with cancer.
Thalidomide
Thalidomide was used in the 1960s as an anxiolytic and antiemetic agent for pregnant women and was withdrawn from use because of its teratogenic effects. Because of its antiangiogenic properties, it has resurfaced as an antineoplastic drug and currently is indicated for the treatment of multiple myeloma.Thalidomide reduces the production of tumor necrosis factor alpha.
Testosterone Replacement
Testosterone is an anabolic steroid hormone that is the primary sex hormone in males. Testosterone replacement is the provision of testosterone to the patient. Testosterone replacement has been studied in patients with cancer for treatment of hot flashes as well as other symptoms.
Tazarotene
Tazarotene is a vitamin A derivative and is also known as a retinoid. This treatment is believed to slow skin cell growth. It comes in a gel or cream available in either 0.05% or 0.1% strength. Tazarotene has been used as an intervention for skin reactions secondary to chemotherapy in patients with cancer.
Targeted Anti-Cytokine Therapy
Targeted anti-cytokine therapy involves the use of an agent, such as a monoclonal antibody, that inhibits physiologic actions of the cytokine. Therapy reviewed here involved the use of an antibody to tumor necrosis factor, which has been used in a variety of inflammatory diseases, such as Crohn’s disease and arthritis. Use of this therapy was evaluated in patients with cancer for the management of fatigue.
Tapentadol
Tapentadol is an opioid similar to tramadol. It is a centrally acting analgesic and a mu-opioid receptor agonist with activity as a norepinephrine reuptake inhibitor. Tapentadol has been examined for effectiveness in relief of chronic pain.