Trazodone
Trazodone is an antidepressant drug that is believed to act by inhibiting serotonin and norepinephrine reuptake. It is approved for use in major depression and has been used off-label for other symptoms, such as panic disorder.
Traumeel S
Traumeel® S consists of multiple homeopathic substances that are expected to have effects on wound healing and inflammation. The formulation contains diluted extacts from Arnica montana, Calendula officionalis, Achillea millefolium, Chamomilla recutita, Symphytum officinale, Atropa belladonna, Aconitum napellua, Bellis perennis, Hypericum perforatum, Echinacea angustifolia, Echinacea purpurea, Hamamelis virginiana, Mecurius solubilis, and Hepar sulfuris. This compound was studied for its effect on oral mucositis.
Transmucosal Opioids
Transmucosal opioids are used to manage breakthrough pain in patients with cancer. These medications include various formulations such as buccal tablets, soluble film, lozenges, and nasal spray. Fentanyl nasal spray is used to treat breakthrough pain in patients aged 18 years or more who take regularly scheduled doses of another opioid. Fentanyl is an opiate analgesic with a relatively short half-life that can be rapidly absorbed via the nasal mucosa.
Transmucosal Fentanyl
Transmucosal fentanyl is a formulation of the opioid fentanyl intended for oral administration that is absorbed directly through the mucous membranes in the mouth. Healthcare professionals should be aware of the different formulations for these medications, the length of their half-life, and the onset of action.
Transforming Growth Factor
Transforming growth factor beta 2 (TGF-beta 2) is a cytokine peptide present in human and bovine milk that plays a role in anti-inflammatory responses and may have beneficial effects on intestinal mucosa and epithelium. TGF-beta 2 dietary supplementation was examined for its effect on radiation-induced diarrhea in patients with cancer.
Transdermal Granisetron
Granisetron is in a class of drugs known as serotonin 5-HT3 receptor antagonists. It works by blocking serotonin activity in the chemoreceptor trigger zone. Granisetron is taken by mouth as a tablet or solution to prevent CINV.
Granisetron may also be administered as a transdermal patch, which is a newer formulation of the drug.
Transdermal Fentanyl
Fentanyl is an opioid analgesic drug. The transdermal delivery system is intended to allow the passive diffusion of the medication over a long period of time while maintaining a constant therapeutic dose. Transdermal fentanyl has been evaluated for the management of chronic cancer-related pain. Transdermal fentanyl also has been examined in relation to opioids by other routes for its effect on opioid-related constipation.
Transdermal Buprenorphine
Buprenorphine is an opioid analgesic used to control moderate to severe chronic pain. This opioid is available in intravenous and sublingual forms; buprenorphine in a trandermal delivery system allows passive diffusion of a consistent dose of medication over a long period. Researchers have evaluated the effectiveness of transdermal buprenorphine for the management of chronic cancer pain.
Transcutaneous Electrical Nerve Stimulation (TENS)/Cutaneous Stimulation
Transcutaneous electrical nerve stimulation (TENS)/cutaneous stimulation is a process involving electrodes placed on the skin over muscles or nerves with a power device generating pulse widths of less than 70 mA (Forst, Nguyen, Forst, Disselhoff, Pohlmann, & Pfutzner, 2004). TENS specifically for patients with cancer has been studied related to pain management.
Transanal Drainage
Transanal drainage is used after an anterior resection for rectal cancer. A tube is inserted to help prevent anastomotic leakage and bleeding after surgery.