Use of Non-Aluminum Containing Deodorant
In the past, whether patients receiving radiation therapy should use deodorant was controversial. Use of metal-containing products has raised questions regarding skin surface doses of the metal that might interfere with external beam radiation delivery. Aluminum-based compounds are generally used as the active ingredient in antiperspirants.
Use of Live Attenuated Vaccines
Live attenuated vaccines contain a form of the living organism that has been weakened so it should not cause disease. There is the possibility that the living microbe in the vaccine could become virulent and cause disease. Examples of live attenuated vaccines are intransal influenza vaccine, varicella vaccine, oral polio vaccine, and the measles, mumps, and rubella vaccine. The potential of attenuated microbes to become virulent is of concern related to prevention of infection among patients with cancer, particularly those who are significantly immunocompromised.
Urokinase IV Catheter Flush
One of the potential mechanisms for development of catheter-related infections is related to the creation of a biofilm in catheter lumens. Urokinase may disrupt biofilms due to its fibinolytic activity. The addition of urokinase to catheter flushing with or without heparin has been examined for its effectiveness in reducing catheter-related infections in patients with cancer.
Urea-Based Topical Treatment
Urea-containing lotion and creams are emollients for topical use and have keratolytic properties. Urea hydrates and breaks down the intercellular matrix, which results in mild debridement and proportion of normal healing of surface lesions. Urea lotion and urea-based products were evaluated in patients with cancer for prevention and management of radiodermatitis and skin effects.
Urea-Based Moisturizer for Kinase Inhibitor-Induced Nail Toxicity
Urea-containing lotion and creams are emollients for topical use and have keratolytic properties. Urea hydrates as well as breaks down the intercellular matrix which results in mild debridement and proportion of normal healing of surface lesions. Urea-based moisturizer was evaluated for its effect on nail toxicities in patients receiving kinase inhibitors. As mechanisms of toxicity with various antitumor agents differ, effects may also differ accordingly.
Urea and Hyaluronic Acid - Topical
Hyaluronic acid, also known as hyaluronate, is a carbohydrate substance that is present in connective, epithelial, and nerve tissues and is a major component of the intracellular matrix. Urea-containing lotion and creams are emollients for topical use and have keratolytic properties. Urea hydrates and breaks down the intercellular matrix, which results in mild debridement and proportion of normal healing of surface lesions. The topical combination of urea and hyaluronic acid was evaluated in patients with cancer for the management of radiodermatitis.
Quetiapine
Quietiapine is an antipsychotic that has been used to treat schizophrenia and biopolar disorder. It is a dopamine, serotonin, and adrenergic antagonist and a potent antihistamine. Quietiapine was studied in patients with cancer for its effect on sleep disturbance.
Oxycodone/Naloxone
Oxycodone is an opiate analgesic. Naloxone is a competitive opioid-receptor antagonist.
Orientation and Information Provision
Orientation and information provision is the act of providing patients and others information about their disease, treatment, and services to be provided. This often includes general information about the organization, staff members with whom the patient may interact, physical structures and layout, and transportation or parking. The intervention differs from psychoeducational interventions in that it is not interactive with patients or families and does not include components such as support or counseling. Orientation and information provision may be done via print or electronic media.
Oral Palonosetron
Palonosetron is an antiemetic agent that is a type of 5HT3 receptor antagonist. This group of agents suppresses nausea and vomiting by inhibiting the binding of serotonin to 5HT3 receptors, which can be found in the chemoreceptor trigger zone in the central nervous system. An oral formulation of this medication was studied for its effectiveness in preventing chemotherapy-induced nausea and vomiting in patients with cancer.